The Definitive Guide to Conolidine alkaloid for chronic pain
Most recently, it has been recognized that conolidine and the above derivatives act over the atypical chemokine receptor three (ACKR3. Expressed in similar spots as classical opioid receptors, it binds to the wide array of endogenous opioids. Not like most opioid receptors, this receptor functions to be a scavenger and would not activate a 2nd mess